MF3 Total Skin Rejuvenation and Revitalization Program (Vegetal Placenta) In November 2007, Laboratoires Dom AVMM AG (Swiss Registration No. CH-170.3.030.727-5), pioneers in Research & Development specialising in in-depth Live Cell Therapy and Placental Therapy went a step further by introducing an additional Vegetal Placenta in 'Cosmeceutical Form' to complement its existing 'Supplement Form' (VP Softgels) range. This New Cosmeceutical Range was researched, developed, manufactured and approved in Switzerland under stringent Swiss GMP (Good Manafacturing Practices) under the name of MF3 of Switzerland Total Skin Rejuvenation & Revitalisation Program.
MF3 of Switzerland Total Skin Rejuvenation & Revitalization Program (Vegetal Placenta) or MF3 VP TSRRP is manufactured according to an unique process, using state-of-the art molecular fractionation technology. The process is performed at controlled temperature with sophisticated ultrafiltration units to allow for the selection of specific molecules and to ensure the maintenance of their potency. The manufacturing steps are performed in accordance with the current provisions for Swiss Good Manufacturing Practice (GMP) ensuring a very high quality product.
The closely guarded Swiss MF3 Vegetal Placenta extraction method via 'Cold Processing' and the special manufacturing process, maintains the bio activeness of the Vegetal Placenta, unlike traditional or conventional methods.
The traditional method used in Asia required constant drying, grounding into powdered form and risked the collection of heavy metals while modern conventional methods of lyophilisation with the application of strong vacuum suction pressure to squeeze water content damages the cell membrane of the placenta. Furthermore, pasteurization or sterilization methods with heat up to 125 C cause changes to the structure of the molecules and dramatically reduces the efficacy of the placentas.
MF3 of Switzerland Total Skin Rejuvenation & Revitalization Program maintains the highest levels of bio activeness and also has the following key features: (See below for further explanation)
These provide amazing skin rejuvenation and anti aging benefits. In an internal physiological scientific study conducted on human volunteers, the cellular turn-over was measured by the DHA method or the disappearance of the skin's artificial color allowing the measurement of the rate of exfoliation and corneocytes turn-over. After using the product diluted at 50% for 11 days, the cellular turn-over had been increased by a minimum of 26%.
MF3 VP TSRRP comes in sets of 10 ampoules, 4 ml each and can be directly applied on the skin (particularly the face and neck area) or preferably injected intramuscularly or intravenously (one ampoule daily).
MF3 VP TSRRP is a composition that will work as anti-MMPs, consolidating the extracellular matrix (ECM) and amino acids that are used to produce new proteins such as collagen in the very specific way skin is structured.
What are Matrix Metalloproteinases (MMPs)? Proteins such as collagen, elastin and others are linked with others macromolecules such as glycoaminoglycans to form the extracellular matrix (ECM) components of all solid body tissues. Examples include cartilage, the fibrous sheaths of muscles, tendons and ligaments, and the dermal layer of the skin. The ECM components are in constant renewal, or turnover, a process based on an equilibrium between synthesis and degradation. Collagen fibers are synthesized by cells such as skin fibroblasts.
In addition to their anabolic activity, chondrocytes and fibroblasts also produce and secrete enzymes known as collagenase or matrix metalloproteinase (MMPs). MMPs represent a special class of enzymes that target and cleave the fibrous proteins of the ECM. Almost paradoxically, chondrocytes and fibroblasts also produce inhibitors of MMPs. These inhibitors are important in restraining the degradative action of MMPs. A balance must therefore exist between these two opposite cellular activities in order to maintain or restore tissues matrix integrity.
MMPs are capable of degrading all kinds of extracellular matrix proteins despite their role in maintaining the integrity of the skin and other tissues, MMPs have also been shown to be involved in angiogenesis (Blood vessel formation, which usually accompanies the growth of malignant tissue).
With aging and in various conditions, the metabolic activity of cells such as fibroblasts may become disturbed. Such a disturbance may affect the equilibrium between production and breakdown of extra cellular matrice (Murphy and Reynolds, 1993). In these conditions, the balance between MMPs and inhibitor of MMPs is no longer respected, so that in most cases, the enzymatic activity of MMPs predominates. Aging and long term sunlight exposures are all factors associated with an increased enzymatic activity of MMPs (Fischer, 1997). This activity eventually leads to the degradation of the collagen fiber meshwork.
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Age-related degradation of the extra-cellular matrix is closely associated with skin wrinkling and sagging. The effects of age-related increase in the activity of MMPs and collagenases is most observable on the skin.
In addition, the premature appearance of wrinkles and sagging are linked to long-term sunlight exposure (Fisher, 1997) and cigarette smoking (Kadunce, 1991).
Aging is a natural and inevitable process. However, the damages caused by age-related degeneration of extra-cellular matrix can be modulated if attempts are made to reestablish and maintain the equilibrium between extra-cellular matrix production and the enzymatic activity of MMPs.
What is GSH?
GSH is the most powerful naturally occurring antioxidant in human beings. It has multiple roles. GSH protects your vision, boosts your immune system, helps turn carbohydrates into energy, and prevents the buildup of oxidized fats. Many clinical studies have shown that GSH may address some of the major health issues of today such as diabetes, heart disease, strokes, asthma, hepatitis and the diseases associated with aging such as Alzheimers and arthritis.
GSH, a small molecule found in almost every cell, is a compound classified as a tripeptide made of three amino acids: L-cysteine, glutamic acid, and glycine. Each and every cell in the body uses these raw ingredients to manufactures GSH. The GSH in each cell has numerous functions. The three most important jobs are antioxidation, immunization boosting and detoxification. GSH is also found in every part of the body, especially the lungs, intestinal tract, and liver. The body produces and stores the largest amounts of GSH in the liver, where it is used to detoxify harmful compounds so that they can be removed from the body through bile. The liver also supplies GSH directly to red and white blood cells in the bloodstream helping keep red blood and white blood cells healthy to maximize the disease-fighting power of the immune system. GSH also appears to have an anti-aging affect on the body. GSH levels decline with age, and a lack of glutathione has been shown to leave the body more vulnerable to damage by free radicals, thus speeding up oxidation (deterioration) of the body.
MF3 VP TSRRP has the best available raw form of GSH and is specially blended with two other active ingredients in a proprietary concoction under specific temperatures and conditions to attain optimum effectiveness with minimum application of heat.
Swiss Authorities Certification
MF3 VP TSRRP is originally manufactured and packed in Switzerland with full conformity to international stringent standards of GMP (Good Manufacturing Practice) and was tested and approved by Swissmedic and obtained the Swiss Public Health Authorities approval.
Main Ingredients Fresh Vegetal Placenta comprises L-Asparagine, L-Threonine, L-Serine, L-Glutamic Acid, L-Proline, L-Alanine, L-Leucine, L-Lysine, L-Arginine, Sodium Chloride, Dextrose, L-Methionine, L-Glutathione, Thiamine, Riboflavine Hydrochlorure, Methylparaben and Puried water.
For Severe Skin Conditions
We recommend 2 boxes of 10 ampoules (vials) each and suggest starting with 1 vial per week (or at least 4-5 day intervals). Gradually increase this up to 2-3 vials per week, so that your body has time to absorb the product. You can inject most of one ampoule and use the rest to apply on the skin with a make-sponge or light cloth, as each ampoule is quite large at 5 ml.
Normal Skin Condition
We recommend 1 box of 10 ampoules (vials) and suggest starting with 1 vial per week (or at least 4-5 day intervals). Gradually increase this up to 2-3 vials per week, so that your body has time to absorb the product. You can inject most of one ampoule and use the rest to apply on the skin with a make-sponge or light cloth, as each ampoule is quite large at 5 ml.
Please note: Due to the potency of the MF3 VP TSRRP formula, it does have a strong smell. Therefore, we recommend applying it before going to sleep. Unused, open ampoules should be sealed with cling film and stored in a cool area. The MF3 VP TSRRP should be used soon after being opened.
Swiss GMP (Good Manufacturing Practice)
Swiss medic Certification No. 06-1258
Swiss Approval No: 07-0371-001 Approval Name: MF3 Total Skin
Rejuvenation & Revitalisation
Program under Swiss Testing STS 347 Swiss Inspection SIS 077
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